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2'-modified nucleosides

home product intermediates 2'-modified nucleosides

2'-deoxy-2'-fluoroadenosine

cas no.:

64183-27-3

molecular formula:

c₁₀h₁₂fn₅o₃

molecular weight:

269.23

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intermediates

purine base pyrimidine base nucleosides nucleotide deoxynucleosides deoxynucleotide anhydro-nucleosides 2'-modified nucleosides arabinonucleosides carbohydrate intermediates of azvudine
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2 '- fluoro-2' - deoxyadenosine can be used as an intermediate in organic synthesis and medicine. it is mainly used in laboratory r & d process and chemical production process.

2 '- deoxy-2' - fluoroadenosine can be used to synthesize 2 '- deoxy-2' - fluoro modified oligonucleotides that can be hybridized with rna. 2 '- deoxy-2' - fluoroadenosine can be effectively cleaved into 2-fluoroadenine (fade) by e. coli purine nucleoside phosphorylase (pnp), which shows good in vivo activity against tumors expressing e. coli pnp.

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